Mass Spectrometry Services

SECIM provides high-throughput global and targeted metabolomic and lipidomic analysis. For further details on prices and to request services, CLICK HERE.

Core PI: Tim Garrett (

R&D Manager: Manasi Kamat (

Global metabolomics and/or lipidomics is performed using state-of-the-art high resolution mass spectrometry (Thermo Q-Exactive) coupled with ultra-high performance liquid chromatography (UHPLC) on serum, plasma, urine, tissue, cells, stool and other samples.

  • LC-MS Metabolomics
  • LC-MS Lipidomics
  • Metabolomics & Lipidomics combo
  • Global plus Tryptophan combo
  • TMAO, choline, betamine

Targeted metabolomics offerings include:

  • Fatty Acids
  • Amino acids
  • Acylcarnitines
  • Resolvins
  • Tryptophan (6 Metabolites)
  • Polyamines
  • Metformin
  • Hydroxytyrosol

These are performed for a variety of matrices including cellular extracts, plasma or tissue using mass spectrometry.  New assays will be developed based on:

  • Demand and/or interest in other metabolite subsets and
  • Follow-up method development to validate putative metabolites identified by prior global metabolomics pursuits.

The targeted metabolomics employs MS with selected reaction monitoring (SRM) using either a direct infusion approach or after chromatographic separation (UHPLC or GC).

Biomarker identification is performed with accurate mass and fine mass resolution, tandem MS (MS/MS) provided by Core 3 and existing metabolomic databases (Metlin, ChemSpider, pubChem). Through constant collaboration, SECIM continues to grow the library of known metabolites.

TO REQUEST SERVICES OR schedule a consultation:

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