LipidQC, a Microsoft Excel-based (MSXL) visualization tool, provides a means – independent of sample preparation methods, MS instruments, and lipid-adduct – to rapidly compare lipid concentration measurements (nmol/mL) with the available consensus mean value estimates for four NIST Standard Reference Materials (SRM): SRM 1950 and the SRM 2378:1–3 series. Users can quickly compare experimental concentrations (nmol/mL) of lipid species quantified for each of the SRM materials listed against the consensus estimates and corresponding uncertainties obtained from the NIST Lipidomics Interlaboratory Comparison Exercise.
Candice Z. Ulmer, Jared M. Ragland, Jeremy P. Koelmel, Alan Heckert, Christina M. Jones, Timothy J. Garrett, Richard A. Yost, and John A. Bowden: LipidQC: Method Validation Tool for SRM 1950 and SRM 2378 Series Using NIST Interlaboratory Comparison Exercise Lipid Reference Values. Analytical Chemistry. (Submitted)