Core 3: Advanced Mass Spectrometry
Core 3 Services
Core 3 provides a range of services for SECIM users focused on unknown metabolite identification, metabolomics methodology development and imaging mass spectrometry.
- Integration of imaging mass spectrometry with global metabolomics, including MALDI/tandem mass spectrometric imaging of small molecules and correlation with MALDI/MS imaging of peptides and proteins
- Biomarker identification in conjunction with Core 1 with accurate mass and high-mass resolution MA and tandem MA (MS/MS), as well as by correlation with NMR chemical shifts in conjunction with Core 2
In addition, Core 3 is actively developing the following areas:
- Innovative isotopic methods for global metabolomics utilizing the IROA (isotope ratio outlier analysis) approach in conjunction with Chris Beecher at IROA Technologies.
- Innovations and improvements in global metabolomics through close interaction with Core 1, including new methodologies, technologies, instrumentation and software