SECIM provides high-throughput global and targeted metabolomic and lipidomic analysis. For further details on prices and to request services, CLICK HERE.
Core PI: Tim Garrett (email@example.com)
R&D Manager: Manasi Kamat (firstname.lastname@example.org)
Global metabolomics and/or lipidomics is performed using state-of-the-art high resolution mass spectrometry (Thermo Q-Exactive) coupled with ultra-high performance liquid chromatography (UHPLC) on serum, plasma, urine, tissue, cells, stool and other samples.
- LC-MS Metabolomics
- LC-MS Lipidomics
- Metabolomics & Lipidomics combo
- Global plus Tryptophan combo
- TMAO, choline, betamine
Targeted metabolomics offerings include:
- Fatty Acids
- Amino acids
- Tryptophan (6 Metabolites)
These are performed for a variety of matrices including cellular extracts, plasma or tissue using mass spectrometry. New assays will be developed based on:
- Demand and/or interest in other metabolite subsets and
- Follow-up method development to validate putative metabolites identified by prior global metabolomics pursuits.
The targeted metabolomics employs MS with selected reaction monitoring (SRM) using either a direct infusion approach or after chromatographic separation (UHPLC or GC).
Biomarker identification is performed with accurate mass and fine mass resolution, tandem MS (MS/MS) provided by Core 3 and existing metabolomic databases (Metlin, ChemSpider, pubChem). Through constant collaboration, SECIM continues to grow the library of known metabolites.